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Anticoagulants: Phenobarbital lowers the plasma levels of dicumarol (name Beforehand used: bishydroxycoumarin) and brings about a lessen in anticoagulant action as calculated via the prothrombin time. Barbiturates can induce hepatic microsomal enzymes causing enhanced metabolism and lowered anticoagulant reaction of oral anticoagulants (e.Period of